Utilisation : Ce produit est destiné uniquement à la recherche.
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P21 5mg
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Voir la politique de livraison →Chaque lot est testé pour sa pureté, sa puissance et sa qualité.
Voir les résultats d’analyse →P21 (Peptide 021) is a synthetic tetrapeptide derived from a fragment of ciliary neurotrophic factor (CNTF), developed for experimental studies on neurotrophic signalling.
Research interest centers on its proposed role in supporting neurogenesis and synaptic function research models, with structural modifications studied for their effect on compound stability and blood-brain barrier permeability characteristics. Research applications include CNTF pathway studies, neurotrophic peptide structure-activity research, and synaptic function investigation.
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3D Molecular Structure
Drag to rotate · scroll to zoom| Chemical Formula | C27H42N6O8 |
|---|---|
| Synonyms | P021, Ac-dggl-adamatanylglycine-NH2, P-21 nootropic peptide |
| Molar Mass | 578.7 g/mol |
| CAS Number | 1246751-68-7 |
| PubChem CID | 56599151 |
| Total Compound Content | 5mg per vial |
| Shelf Life | 36 months |
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
What is the relationship between P21 and the parent CNTF protein in neurotrophic signalling research?
P21 is a synthetic peptide derived from a fragment of ciliary neurotrophic factor (CNTF), a signalling protein involved in neuronal growth, differentiation, and survival pathways. Research with P21 focuses on determining whether this smaller peptide fragment can reproduce selected downstream signalling effects associated with CNTF while providing a simplified tool for studying neurotrophic pathway regulation.
What structural modifications were incorporated into P21's design?
P21 incorporates modifications to the native CNTF-derived fragment that have been investigated for their effects on peptide stability and tissue distribution. Comparative structure-activity studies examine how these modifications influence degradation resistance, signalling activity, and overall experimental utility relative to unmodified peptide fragments.
What experimental endpoints are used to study P21's proposed effects on neurogenesis and synaptic function?
Research commonly utilizes neural cell culture systems to evaluate neurogenesis-associated biomarkers, neuronal differentiation markers, synaptic protein expression, and signalling pathways related to neuronal plasticity. Additional endpoints may include measurements of neurite outgrowth, cellular maturation, and electrophysiological markers of synaptic activity to characterize effects on neural network function.
