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4’-DMA-7,8-DHF ( Eutropoflavin ) 10mg / 60 capsule
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Vedi i risultati di laboratorio →4'-DMA-7,8-DHF, also designated Eutropoflavin, is a synthetic flavonoid derivative studied for its potential to modulate TrkB receptor activity. Research interest centers on its role in peptide-receptor signalling cascades, neurotrophic factor analogue research, and downstream kinase pathway investigation in controlled laboratory environments.
Research applications include TrkB receptor pharmacology, neurotrophic signalling pathway studies, and comparative flavonoid receptor-modulator research.
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3D Molecular Structure
Drag to rotate · scroll to zoom| Chemical Formula | C17H15NO4 |
|---|---|
| Synonyms | Eutropoflavin, 4'-Dimethylamino-7,8-dihydroxyflavone, 2-(4-(Dimethylamino)phenyl)-7,8-dihydroxy-4H-chromen-4-one, 4'-DMA-7,8-DHF |
| Molar Mass | 297.30 g/mol |
| CAS Number | 1205548-04-4 |
| PubChem CID | 44610701 |
| Total Compound Content | 600mg (10mg per capsule) |
| Shelf Life | 36 months |
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Q: What cell-based assays are used to study 4'-DMA-7,8-DHF's proposed TrkB receptor modulating activity?
Cell lines expressing TrkB receptor constructs are used in receptor engagement and downstream signalling assays, typically measuring receptor dimerization, autophosphorylation status, and activation of downstream kinase cascades following compound exposure. Comparative assays against established neurotrophic factor reference standards allow researchers to characterise the relative signalling profile produced by 4'-DMA-7,8-DHF exposure within the TrkB receptor research framework.
How does 4'-DMA-7,8-DHF's flavonoid structure relate to its proposed receptor-modulating research profile?
As a structurally modified flavonoid derivative, 4'-DMA-7,8-DHF is studied within structure-activity relationship research examining how specific substitutions on the flavone scaffold influence receptor interaction characteristics. Comparative research across structurally related flavonoid compounds allows investigation into which structural features are associated with TrkB pathway engagement, informing broader flavonoid-class receptor pharmacology research.
What downstream kinase pathway readouts are used in 4'-DMA-7,8-DHF receptor signalling research?
Western blot and phospho-specific antibody assays measuring activation status of downstream kinase intermediates in receptor signalling cascades are standard readouts used in cell-based models following compound exposure, allowing researchers to characterise which signalling branches are engaged. These molecular readouts are typically paired with functional cellular assays relevant to the specific research model under investigation.
