Uso del producto: Este producto está destinado exclusivamente a la investigación.
Toda la información de los productos de este sitio web tiene fines exclusivamente educativos. Cualquier forma de introducción en el cuerpo de personas o animales está estrictamente prohibida por la ley. Este producto solo debe ser manipulado por profesionales autorizados y cualificados. No es un medicamento, alimento ni cosmético y no debe etiquetarse, utilizarse ni presentarse como tal.
Coluracetam – Powder, 1 gram
Durante el cambio de envase, puedes recibir productos con la etiqueta anterior o con la nueva. La formulación, la pureza y la calidad siguen siendo exactamente las mismas, según nuestros estándares.
- Tarjeta de crédito
- Transferencia bancaria (SEPA inmediata)
- Transferencia bancaria (ACH)
- Wise
- Revolut
- Zelle
- Remitly
- Western Union
- Chime
- Otros
-25% en todo – hasta el 31 de octubre
25% sobre los precios habituales, en sustitución de otras ofertas. Acumulable solo con el descuento crypto.
Envío en el día para pedidos en EE. UU. realizados antes de las 12:00 EST.
Ver la política de envíos →Devoluciones sin complicaciones en 30 días para productos sin abrir.
Ver la política de devoluciones →Cada lote se analiza para comprobar su pureza, potencia y calidad.
Ver resultados de laboratorio →Coluracetam (MKC-231) is a synthetic compound incorporating a tetrahydrofuroquinoline ring system fused to a pyrrolidinone-derived acetamide substituent, structurally related to but distinct from simpler racetam-class compounds.
Research interest centers on its proposed effects on high-affinity choline uptake (HACU) in cholinergic neuronal models, including reported activity in HACU-impaired model systems. Research applications include cholinergic transporter pharmacology, HACU restoration studies, and structure-activity relationship research within the furoquinoline-acetamide compound series.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
3D Molecular Structure
Drag to rotate · scroll to zoom| Chemical Formula | C19H23N3O3 |
|---|---|
| Synonyms | Coluracetam 135463-81-9, N-(2,3-dimethyl-5,6,7,8-tetrahydrofuran[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide, MKC-231 |
| Molar Mass | 341.4 g/mol |
| CAS Number | 135463-81-9 |
| PubChem CID | 214346 |
| Total Compound Content | 1 gram |
| Shelf Life | 36 months |
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
How does coluracetam's effect on HACU in impaired model systems differ from its activity under baseline conditions?
Research distinguishes coluracetam's reported capacity to restore choline uptake function in experimentally HACU-impaired cell or synaptosome models from simple potentiation of normally functioning choline transport. This distinction is investigated using paradigms that first chemically or genetically impair HACU activity (establishing a reduced-function baseline) before assessing whether coluracetam exposure restores uptake kinetics toward normal-function levels, a different experimental question than measuring potentiation above an already-normal baseline.
What structural features distinguish coluracetam from classical pyrrolidinone-only racetam compounds?
Coluracetam retains a 2-oxopyrrolidinone acetamide substituent characteristic of the racetam family but appends this to a tetrahydrofuroquinoline ring system, a considerably more complex polycyclic structure than the simple substituents found on piracetam, oxiracetam, or pramiracetam. This structural distinction is relevant to structure-activity relationship research examining whether choline-uptake-modulating activity depends primarily on the shared pyrrolidinone-acetamide moiety or is influenced by the broader molecular scaffold to which it is attached.
What assay formats quantify coluracetam's effects on the high-affinity choline transporter?
Radiolabeled choline uptake assays in synaptosome preparations or in cell lines expressing the high-affinity choline transporter (CHT1) are the standard quantitative method, allowing determination of uptake kinetic parameters (Km, Vmax) under coluracetam exposure relative to vehicle control. These assays are often run in parallel with HACU-impairment paradigms (e.g. using a choline transport inhibitor reference compound) to specifically test coluracetam's restorative versus potentiating activity profile.
